AI and COVID19
Implications on healthcare and society
(or something close to that)
Presentation by Ali Tarraf, April 2020
- 1. Get you excited about the potential of AI
- 2. Show the Implications of AI in Healthcare
- 3. Connect you with like minded folks
- 1. A Red bold Q means it is a question up for discussion on twitter and zoom:
- 2. We will use twitter as an interactive platform for Q&A. Please go to @BeirutAI twitter page to
share your responses to posted questions and make sure to TAG us @BeirutAI and use the HASHTAG #AICOVID19.
- 3. We will be streaming live on facebook and accepting questions from the general audience.
- 4. This is an online discussion, so orderly interruptions are welcomed! "Raise your hand" on zoom to participate in the discussion.
- Intro Beirut AI
- AI Overview
- AI & Covid19
- How can you help?
Intro Beirut AI
- Who we are?
- What we do?
We are part of the City AI movement
What We do?
We bridge AI & Business
Are you coming from an AI/engineering background or healthcare medical professional?
Are you interested in improving your AI technical or managerial skills?
- What is AI?
- Why is it a big deal?
- AI applications
Digital Technology Waves
Q:What is artificial intelligence?
A. It is the science and engineering of making intelligent machines, especially intelligent computer programs,
but AI does not have to confine itself to methods that are biologically observable.
Q. Yes, but what is intelligence?
A. Intelligence is the computational part of the ability to achieve
goals in the world. Varying kinds and degrees of intelligence occur in people, many animals
and some machines.
Is the human existence headed towards a Dystopia or a Utopia, or nothing will change?
Ranges of possible futures
What preposterous future can you imagine? What possible future can you imagine?
AI New Social Contract
Within fifteen years I predict that we will technically be able to automate 40 to 50 percent of all jobs in the United States.
- Dr Kai Fu Lee
What can our Society do to combat the shift in jobs from humans to machines?
Leisure as the basis of culture
Of course the world of work begins to become - threatens to become - our only world, to the exclusion of all else.
The demands of the working world grow ever more total, grasping ever more completely the whole of human existence.
- Joseph Pieper
Joseph Pieper argued in 1948 that our society should shift to Leisure as the basis of culture. Is that a preferable solution?
Back to the Present: AI as a growth engine
AI can unlock True Factor Productivity (TFP) of economies and become an engine of growth.
PPAID: AI Business Value Equation
Value Captured = People x
If you want to get paid, make sure you are strong in all aspects of PPAID.
Your benefits will be as good as your weakest link.
Can you think of an AI applications that didn't live up to the hype? Why do you think its value fell short?
Data to Decision
AI Technology will feed on data to empower the automation of human decisions to actions.
AI Applications examples[1/4]
Descriptive - What happened?
18 % of Covid19 patients were asymptomatic on the Covid19 afflicted Princess Ship
AI Applications examples[2/4]
Diagnostic - Why did it happen?
Correlation between number of McDonald restaurants and Covid19 cases count.
Does correlation imply causation? Is there more cases in the USA because
of higher number of McDonalds restaurants?
AI Applications examples[3/4]
Predictive - What will happen?
Up to 2million fatalities of Covid19 worldwide
AI Applications examples[4/4]
Prescriptive - What can we do?
Deny access to metro if your phone says you are not respecting social distancing.
AI & Covid19
- Covid19 World Shakedown
- AI Applications to Covid19
A new world order
Covid19 is ushering a global recession and enforcing new "normal" way of life
It took 30kb or 5000 words to...
...Impact the life of billions of humans
What can you express or create in 500 lines of words that will have world wide impact?
AI & Covid Applications
- Patient Scale
- Molecular Scale
- Society Scale
- Social Distancing
- Protein Structure Prediction
- Improving Viral Dna Testing
- Drug Repurposing
- Drug Discovery
- Medical Imaging for Diagnosis
- Non Invasive measurement for disease tracking
- Patient Outcome Prediction
Starting with Medical Imaging for Diagnosis
Binary Classification CT Scans
Chen et al trained 6000ct scans labeled by radiologist and deployed model to Renmin Hospital of Wuhan University.
Multiple Classification CT Scans
Model improved performance and reduced time of radiologist review from 30 to 5min.
This is a
promising model to compliment radiologists.
Non Invasive Measurement For Disease Tracking
Kinect depth camera to identify respiratory patterns. Covid patients display tachypnea,
Potential to be used as a first order screening for covid19.
Phone sensors to detect Covid19
A Novel AI-enabled Framework to Diagnose Coronavirus COVID-19 using Smartphone
Contact Tracing Apps
Contact tracing app to detect covid19 through surveys and location data
Patient Outcome Prediction
Predict Mortality & Hospitalisation
Predict high risk patient mortality from key clinical indicators. Advantage is interpretability since
indicator correspond to pathophysiological progress of covid19.
Protein Structure Prediction
Protein 3D Structure
Alphafold estimates distances & angles between aminoacids which is used to characterize the shape of the protein.
Improving Viral DNA Testing
SHERLOCK RNA detection
CRISPR-Cas13 is an RNA editing technique that can alter protein sequences without
modifying the genome in a cell. Using Cas13,
SHERLOCK (specific high-sensitivity enzymatic reporter unlocking) was developed to detect viruses.
AI can help SHERLOCK Assays
AI can help identify the appropiate testing procedures to be able to detect viruses
Biomedical Knowledge Graphs
Benevolent AI used
Natural Language Processing to find relationships like "gene X is biologically
associated with disease Y".
They found that Baricitnib for rheumatoid arthrithis makes it harder for virus to enter the boost cell by
inhibiting ap2 protein kinase.
BERE:Biomedical Entity Relation Extraction Network
BERE trained on 700k documents and can find valid "Drug to
Predicting Commercial Drugs Inhibitory Potency
The research team used pretrained deep learning-based drug-target interaction model called Molecule Transformer-Drug Target
Interaction (MT-DTI) to identify commercially available drugs that could act on viral
proteins of 2019-
The result showed that Atazanavir, an antiretroviral medication used to treat and prevent the
human immunodeficiency virus (HIV), is the best chemical compound, showing a inhibitory potency with
Kd of 94.94 nM against the 2019-nCoV 3C-like proteinase.
MT-DTI AI model
Will the Drug (left) interact with the targeted protein (right)?
MT-DTI allows you to predict an affinity score ONLINE!
MT-DTI Online Demo
...Using Reinforcement Learning
Deep Q-learning network for drug design
The SIR Model
AI forecasting of Cases
Teams are curating specific news content related to the virus and perform both
manual and automated fact-checking against WHO.
Video Social Tracking
Using distance measured between walkers from video cameras, it is possible to identify bottlenecks where social distancing cannot be maintained,
and how citizens adapt as restrictions are imposed or lifted.
Using pedestrian sensors data on roads, deep learning algorithm makes it possible to monitor the local response of citizen at each traffic intersection with lockdowns and other policies.
Big Data Phone location
Tectonix analysed billions of anonymous phone records to monitor if people are abiding by government mobility policies.
How Can You Help?
- Technical track
- Business track
I hope you have learned something new today!
Reach out to us on social media...
Presentation by Ali Tarraf, April 2020